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Precursor B-cell ALL cells typically express CD10, CD19, and CD34 on their surface, along with nuclear terminal deoxynucleotide transferase (Td T), while precursor T-cell ALL cells commonly express CD2, CD3, CD7, CD34, and Td T.

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B- and T-cell lymphoblastic leukemia cells express surface antigens that parallel their respective lineage developments.

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ALL (also called acute lymphocytic leukemia) is an aggressive type of leukemia characterized by the presence of too many lymphoblasts or lymphocytes in the bone marrow and peripheral blood.

It can spread to the lymph nodes, spleen, liver, central nervous system (CNS), and other organs. Signs and symptoms of ALL may include the following: ALL occurs in both children and adults. (Refer to the PDQ summary on Childhood Acute Lymphoblastic Leukemia Treatment for more information about ALL in children.) ALL presumably arises from malignant transformation of B- or T-cell progenitor cells.[2] It is more commonly seen in children, but can occur at any age.




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